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首頁(yè) /診斷試劑 /用藥指導(dǎo)標(biāo)準(zhǔn)品 /伊立替康UGT1A1多態(tài)性 /UGT1A1*37 Reference Standard

UGT1A1*37 Reference Standard

CBPA0018

產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction  
Format Genomic DNA
Description UGT1A1, UDP-glucuronosyltransferase 1-1, is an enzyme that catalyzes the glucuronidation of substances to soluble metabolites for excretion (PMID: 28520360). Genetic polymorphisms in UGT1A1 may alter the metabolism of chemotherapy drugs such as irinotecan, resulting in severe toxicity.
   
Technical Data 
Gene UGT1A1
AA Change N/A
DNA Change N/A
Chr position (GRCh38) NC_000002.12_g.233760233_233760234insTATA
Allelic Frequency 50%
Zygosity Heterozygous
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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