PTEN p.K128_R130del Reference Standard
CBP10717
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | |
| Gene | PTEN |
| Description | PTEN K128_R130del results in the deletion of 3 amino acids in the phosphatase tensin-type domain of the Pten protein from amino acids 128 to 130 (UniProt.org). K128_R130del confers a loss of function on the Pten protein as indicated by failure to regulate glucose uptake and to dephosphorylate AKT in cell culture. |
| Technical Data | |
| DNA Change | c.383_391del |
| AA Change | p.K128_R130delAAGGGACGA |
| Mutation type | Deletion - In frame |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000371953.3 |
| Cosmic ID | COSM4967 |
| Chr position | chr10-87933141-AAGGGACGA(9bp)_hg38 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
